RNA in situ hybridization: Journal Clinical Investigation, June 2016

Dr. Ann Fu performed in situ hybridization for LINC00473 using an ACD RNAScope customized probe with Dr. Lizi Wu (cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth, JCI 2016).  Enhanced LINC00473 expression was highly correlated with LKB1 mutational status and was associated with poor survival in human lung adenocarcinoma.