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Microscopy

VS200 Brightfield&Fluorescence Slide Scanner Installed November 2023

The VS200 slide scanner was obtained through an NIH Shared Instrumentation Grant and has been installed in D11-35.  Assisted scanning will be performed by MPC staff and charged on a per-slide cost basis. Unassisted use can be performed following training. The VS200 produces fast scans at 20x or 40x in…

New Core member of BioImaging North American (BINA)

MPC has joined the BioImaging North American (BINA) consortium. BioImaging North America (BINA) was started during the 2018 “Frontiers in Microscopy Technologies and Strategies for Bioimaging Centers Network” meeting on Janelia Research Campus. It was registered as a US non-profit organization in June 2018 and until the Spring of 2021 was…

MPC provides special staining services

MPC provides special staining services, including PASD, Masson’s Trichrome, and others. Please contact us for more information. PASMasson’s TrichromeOil Red OPicrosirius RedSafranin O…

Mouse Aorta Stained With H&E

Our users often request special services for sectioning or staining. On this particular project, mouse aorta is shown by H&E stain.  (Mouse aorta stained with hematoxylin and eosin)      …

New Customer Feedback Form

We, the Molecular Pathology Core, have recently added a Customer Feedback Form to our website. We want to hear back from our submitters. We encourage you to fill out a feedback form to let us know what you think of our services.  …

Laser microdissection for pancreatic cancer- Song Han et al, July 2016

A recent publication by University of Florida investigators highlights the utility of laser microdissection to separate pancreatic ductal epithelium and stroma. Dr. Song Han and colleagues published their studies in Oncotarget describing alterations in miRNA important in pancreatic tumor biology. Laser microdissection was performed by Dr. David Gonzalo, Chief Gastrointestinal…

RNA in situ hybridization: Journal Clinical Investigation, June 2016

Dr. Ann Fu performed in situ hybridization for LINC00473 using an ACD RNAScope customized probe with Dr. Lizi Wu (cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth, JCI 2016).  Enhanced LINC00473 expression was highly correlated with LKB1 mutational status and was associated with poor survival in human lung…

Diabetes March 2016 Cover Image

Dr. Campbell-Thompson and colleagues recently published an article on the immunophenoytyping of islet inflammation and residual beta cell mass in organ donors with type 1 diabetes in the March, 2016 issue of Diabetes. One of their images was selected for the  journal’s cover. The multiple immunofluorescence staining was done by…

Laser Capture Microdissection- Leica 7000

The Leica 7000 is now available for brightfield and fluorescence sample microdissection. Paraffin and frozen samples can be used with nuclei acid isolation. Numerous options are available including live cell capture. Please contact Dr. Ann Fu to discuss your project needs and arrange use.