Our mission is to improve human and animal health by accelerating research using histology and microscopy procedures.
The Molecular Pathology Core (MPC) is based in the Experimental Pathology Division of the Department of Pathology, Immunology, and Laboratory Medicine and opened January 1, 2001. We can be referenced using RRID:SCR_016601.
MPC is a comprehensive histology and microscopy facility for paraffin and frozen blocks and for all aspects of specimen collection, preparation, fixation, processing, staining, and analysis.
As a shared histology core, we strive to help researchers so they can concentrate on the science.
- Processing and sectioning of frozen or fixed samples of tissues, cells, and plants by cryostat, microtome and vibratome
- Staining methods including routine and special histology stains or immunolocalization of proteins/RNA/DNA (IHC/IF/ISH/FISH)
- Additional specialized services include whole slide images (brightfield), tissue microarray construction, laser microdissection, and Nanostring GeoMX digital spatial profiling.
- Rental equipment include cryostat, microtomes, vibratome, microscopes (brightfield and fluorescent) and image analysis workstation with multiple programs.
- Services are available to all investigators and consultations are welcomed.
For those using the Leica 7000 LMD microscope, please include the following: “This work utilized a LEICA 7000 laser microdissection microscope purchased with an NIH shared instrumentation grant 1S10OD016350-01.”
Please consider acknowledging Core services using “Molecular Pathology Core at the College of Medicine, University of Florida”, and names of staff members instrumental in your work. Please consider authorship when our staff members contribute significantly to the development of your experimental design or to your publication content.