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Molecular Pathology Core

MPC Staff Contribute to Biomaterials Advances Publication on Aptamer-Functionalized Hydrogels

We are pleased to highlight a recent publication by Dr. Nikolaos Pipis in Biomaterials Advances (Elsevier), titled “Injectable aptamer-functionalized nucleic acid–collagen hydrogels as a bioactive platform for angiogenic applications.” This work represents the culmination of Dr. Pipis’s doctoral research at the University of Florida and presents the first in vivo…

VS200 Brightfield&Fluorescence Slide Scanner Installed November 2023

The VS200 slide scanner was obtained through an NIH Shared Instrumentation Grant and has been installed in D11-35.  Assisted scanning will be performed by MPC staff and charged on a per-slide cost basis. Unassisted use can be performed following training. The VS200 produces fast scans at 20x or 40x in…

New Core member of BioImaging North American (BINA)

MPC has joined the BioImaging North American (BINA) consortium. BioImaging North America (BINA) was started during the 2018 “Frontiers in Microscopy Technologies and Strategies for Bioimaging Centers Network” meeting on Janelia Research Campus. It was registered as a US non-profit organization in June 2018 and until the Spring of 2021 was…

Bon Voyage Lily and Welcome Eric

In August, we bid a fond farewell to Xian (Lily) Li, postdoctoral fellow, in the Core for two years, who returned to China. She worked tirelessly to provide histology and immunohistology services to our users, particularly during the 2020 pandemic. We hope she can return to the Core in a…

MPC provides special staining services

MPC provides special staining services, including PASD, Masson’s Trichrome, and others. Please contact us for more information. PASMasson’s TrichromeOil Red OPicrosirius RedSafranin O…

MPC Introduces Tissue Micro Array

Molecular Pathology Core now offers the construction of Paraffin Tissue Micro Array (TMA) blocks.  TMA blocks are constructed out of the area of interest from the “donor” block and placed into the “recipient” block which becomes the TMA.  A 36 core and a 72 core TMA option are available. Contact…

Mouse Aorta Stained With H&E

Our users often request special services for sectioning or staining. On this particular project, mouse aorta is shown by H&E stain.  (Mouse aorta stained with hematoxylin and eosin)      …

Quadruple IHC Stain

Quadruple or multiplex IHC is becoming more mainstream. Shown below are islets from three species (human, rat, and pig) stained for somatostatin (SS, green), glucagon (GCG, red), insulin (Ins, blue) and pancreatic polypeptide (PP, black). This staining was done using OPAL chromogen kits given to the MPC by Biocare Medical.

New Customer Feedback Form

We, the Molecular Pathology Core, have recently added a Customer Feedback Form to our website. We want to hear back from our submitters. We encourage you to fill out a feedback form to let us know what you think of our services.  …

Laser microdissection for pancreatic cancer- Song Han et al, July 2016

A recent publication by University of Florida investigators highlights the utility of laser microdissection to separate pancreatic ductal epithelium and stroma. Dr. Song Han and colleagues published their studies in Oncotarget describing alterations in miRNA important in pancreatic tumor biology. Laser microdissection was performed by Dr. David Gonzalo, Chief Gastrointestinal…